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Acquired Hemophilia

When used as first treatment, NovoSeven® RT was shown to be effective in stopping bleeds from acquired hemophilia

What is acquired hemophilia?

Acquired hemophilia Acquired hemophilia
A form of hemophilia in which the body starts producing antibodies that fight its own blood-clotting proteins. is a rare but dangerous blood disorder. Each year, it occurs in 1 - 1.5 of 1 million people. Acquired hemophilia is associated with the following:

  • The body’s natural clotting Clotting
    The process of forming into a clot or clots.     process is disrupted
  • The body produces antibodies Antibodies
    Cells of the immune system that fight and destroy viruses and bacteria that can cause infection.     that fight its own blood-clotting Blood-clotting
    Also known as coagulation. It is the process of turning some of the elements in the blood into a clot. Blood-clotting is the result of a sequence of actions and reactions that involve several different proteins in the blood.     proteins
  • The condition can lead to spontaneous Spontaneous
    Something that happens on its own, for what seems like no reason. Spontaneous bleeding does not appear to have a specific cause.     , uncontrolled bleeding, most often in the skin and soft tissues
  • It can occur in men and women with no personal or family history of bleeding

Symptoms and diagnosis of acquired hemophilia

Acquired hemophilia is hard to detect. The most common symptoms are:

  • Bleeding into the skin
  • Bleeding into soft tissues
  • Internal bleeding Internal bleeding
    Bleeding inside the body, in tissues or organs.

Unlike classic hemophilia Classic hemophilia
Another name for hemophilia A, the most common type of hemophilia. , patients with acquired hemophilia do not usually have joint bleeds Bleeds
In hemophilia, a collection of blood in an area, such as a muscle or joint. . However, bleeding into skin and soft tissues can be serious.

Acquired hemophilia is diagnosed with laboratory tests that measure clotting time Clotting time
The time required for blood to clot. and Factor VIII Factor VIII
One of the 13 clotting factor proteins that help form blood clots. levels.